Question: You determine that a particular gene in a peson with a genetic disease is the same size as that of a healthy individual.

Question: You determine that a particular gene in a peson with a genetic disease is the same size as that of a healthy individual. You suspect that the arises from a point mutation (a single nucleotide change that results in a defect in the protein.) Describe a how you could confirm this hypothesis.

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Comment: We learned about Sanger Sequencing and Next Gen sequencing in class. Could you use either of these and if yes why would you use one over the other.

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Point mutations that occur in non-coding sequences are usually without any results, although there are exceptions. If the mutated base pair is in the promoter sequence of a gene, then the expression of the gene could change. If the ba...

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